ACTH: adrenocorticotropic hormone; DEXA: dual-energy X-ray absorptiometry; DM: diabetes mellitus; FSH: follicle-stimulating hormone; HbA1c: glycated hemoglobin; LH: luteinizing hormone; FT4: free thyroxine; TSH: thyroid-stimulating hormone; UFC: urinary free cortisol. This evidence concerns the gene POMC and diabetes mellitus.