The findings from qRT-PCR, WB, and ELISA experiments confirmed that the mRNA and protein expression levels of the hub PRGs (CASP1, IL1B, IL18, IL6, NLRP1, NLRP2, NLRP3, and TNF) were considerably upregulated in human AAA samples compared to normal samples. Here, NLRP3 is linked to triple-A syndrome.