Their experiments for the first time demonstrated that Mv-3-gal could remarkably induce G1/S phase cell arrest and apoptosis of human HCC cell Huh-7 cells via regulating p38/Jun N-terminal kinase (JNK)/ERK MAPK and protein kinase B (Akt)/phosphatase and tensin homolog (PTEN) signal pathways. Here, AKT1 is linked to hepatocellular carcinoma.