TLR4 and metabolic dysfunction-associated steatohepatitis: GEN could ameliorate hepatic inflammatory reaction in nonalcoholic steatohepatitis (NASH) rats, possibly by reducing TLR4 protein and gene expression, decreasing the endotoxin and TNFα, alleviating the inflammatory reaction and making the indicators detected in blood and liver stay near normal in NASH rats (Yin et al., 2019).