Administration of AP (10, 20, and 40 μM) decreased the spheroid-forming ratio, upregulated expression of src homology region 2 domain-containing phosphatase 1 and suppressed the phosphorylation of signal transducers and activators of transcription 3 (STAT3) protein in human liver cancer MHCC97H cells in a dose-dependent manner (Cui et al., 2018). The gene discussed is STAT3; the disease is liver cancer.