In addition, DM patients who carry at least one minor allele (A) of SDF-1 rs1801157 (GA and AA; AOR, 2.156; 95% CI, 1.051-4.424; p=0.036) are more commonly suffering from CKD than are those homozygotes for the major allele (GG) in dominant model. This evidence concerns the gene CXCL12 and diabetes mellitus.