In the current study, we enrolled the GRIm score, NLR, age, BMI, family history, basic disease, menarche age, menopause, ALT, AST, AST/ALT, LDH, ALB, TBIL, CA153, CEA, D-D, FBG, white blood cell, neutrophil, lymphocyte, monocyte, platelet, tumor size, pathological TNM stage, TALN, PALN, molecular subtype, chemotherapy, radiotherapy, endocrine therapy, targeted therapy to construct the univariate and multivariate COX analysis. The gene discussed is CEACAM5; the disease is neoplasm.