In view of the results, we found that QCT affected a serious of biological processes including cellular response to nitrogen compound, cellular response to organonitrogen compound, response to inorganic substance, positive regulation of phosphate metabolic process, positive regulation of phosphorus metabolic process et al. Moreover, we found that the most significantly enriched KEGG pathways were pathways in cancer, fluid shear stress and atherosclerosis, Lipid and atherosclerosis, AGE-RAGE signaling pathway in diabetic complications, proteoglycans in cancer. Here, RENBP is linked to atherosclerosis.