NGF and cancer: The neural innervation of multiple cancers (prostate, G.I., lung), including nerve growth factor, and the dynamic interactions between nerve innervation and cancer progression provides an extraordinary opportunity for clinical translation [Hutchings et al., 2020] but also there is the caveat that the inverse correlation between innervation and outcome of these tumors, vagal stimulation could be a double-edged sword, and theoretically even spur growth [Hutchings et al., 2020].