Furthermore, seropositive IP had higher frequencies of EBV-specific CD8+ polyfunctional cells than seronegative IP in two other subsets: CD8+CD107a+IFNɣ+IL2-TNFɑ- and CD8+CD107a+IFNɣ-IL2-TNFɑ+. Here, CD8A is linked to incontinentia pigmenti.