As shown in Figure 3A, the expression of HLA-G and PD-L1 was significantly higher in EVs isolated from NB samples (MRFI, median ± SE: 3.65 ± 2.68, and 53.06 ± 19.51, respectively) than in controls (2.58 ± 0.27 and 14.23 ± 6.60, respectively). Here, HLA-G is linked to neuroblastoma.