Additionally, MDA5+ DM patients displayed more than one cell cluster with high expression of interferon genes (IFIT1, IFIT2, IFIT3, IFI44, IRF7, IFI127, IFIH1, IFI27 and IF16), as well as interferon-stimulated genes (MX1 and MX2). The gene discussed is IFI27; the disease is dermatomyositis.