LVMI was positively associated with diabetes duration, age, hypertension history, SBP, using of DDP‐4i, CCBs, WC, WHR, VFA, SFA, VFA/H2, VFA/weight, BUN, Cr, and baPWV, but negatively associated with using of thiazolidinediones, insulin, and e‐GFR in both males and females. The gene discussed is INS; the disease is Hypertension.