Additionally, significant differences were noted in age (p < 0.0001), education level (p < 0.0001), APOE ε4 carrier status (p < 0.0001), cardiometabolic variables including systolic BP (p < 0.0001), BMI (p < 0.0001), diabetes prevalence (p < 0.0001), LDL cholesterol (p < 0.01), and total cholesterol (p < 0.01) across the four groups (Table 2). Here, APOE is linked to diabetes mellitus.