We found a prevalence of current MDD (15.5%, 8 scores cut-off and 8.6%, 10 scores cut-off among girls and 3.7%, 8 scores cut-off and 2.1%, 10 scores cut-off among boys) and GAD (25.0%, 5 scores cut-off and 8.4%, 10 scores cut-off among girls and 10.3%, 5 scores cut-off and 1.6%, 10 scores cut-off among boys) in Mozambique, which in terms of females seemed to be similar to among adolescents and youth seeking psychological services in Mozambique (7.3% had PHQ-9, ≥ 11 scores), 9% had GAD-7, ≥ 10 scores) [13], and among school adolescents in Maputo (17.7% GAD, and 8.5% MDD) [11]. This evidence concerns the gene GAD1 and generalized anxiety disorder.