Moreover, NKp30 and NKp44 engagement with cancer cells can induce NK cell death via the upregulation of Fas Ligand in certain tumors.220 Surprisingly, overexpression of NKp44 in NK-92 was shown to inhibit activation after binding of NKp44 to PCNA, which is widely overexpressed in tumor cells.221,222. Here, NCR2 is linked to cancer.