Three of these were related to tumor/lymphocyte proximities (Tm_T.SPS, Tm_CD8nT.SPS, Tm_Treg.SPS) and 5 were related to PD-1/PD-L1 proximities (PD1T_PDL1.SPS, PD1T_PDL1Im.SPS, PD1Tc_PDL1.SPS, PD1Tc_PDL1Im.SPS, CD8nPD1T_PDL1Im.SPS). This evidence concerns the gene PDCD1 and neoplasm.