Elevated NT-proBNP was found to have good discrimination ability to identify those at risk of future endpoints, with C index that ranged from 0.80 (95% CI 0.74, 0.86) for CVD, to 0.83 (0.76, 0.90) for CHD, to 0.88 (0.81, 0.94) for AF, and was highest for CHF at 0.89 (0.83, 0.95) (Fig. 1). This evidence concerns the gene NPPB and coronary artery disorder.