SIRT1 and ischemia: Studies have indicated that after intestinal ischemia-reperfusion, the intestinal AMPK-Sirt1 autophagy pathway is activated, and propofol further activates this pathway, alleviating intestinal injury, suppressing cell apoptosis, reversing inflammation and oxidative stress, improving the 24-hour survival rate of rats post intestinal ischemia-reperfusion, and mitigating intestinal injuries (Liu et al. 2022a, b).