As shown in Fig. 2, ingenuity pathway analysis (IPA) detected downregulation of many canonical pathways related to growth and cancer, including Wnt/β‐catenin, EGF signalling, TGF‐β signalling as well as repression of inflammatory pathways such as TNFR1 signalling, TNFR2 signalling and IL‐6 signalling. The gene discussed is TNFRSF1A; the disease is cancer.