To elucidate the mechanisms by which the miR-936/Pim-3 axis inhibits sorafenib resistance in liver cancer, the mRNA expression profiles of GV102-Pim-3-shRNA-Huh7/SOR vs. Huh7/SOR, and GV102-Pim-3-shRNA-HepG2/SOR vs. HepG2/SOR cells were analyzed using the Affymetrix ClariomTM S GeneChip (Figures 3A, B). Here, PIM3 is linked to liver cancer.