Regarding KLRB1, our findings align with those of Jiu-Ling Chen and other researchers, who discovered that KLRB1 was a tumor suppressor gene suggestive of a better prognosis, and that KLRB1 expression was positively correlated with the level of CTLs, B cells and DCs (76, 77). Here, KLRB1 is linked to neoplasm.