The outcome is iron-restricted erythropoiesis, followed by the development of anaemia of chronic disease (ACD) with an elevated ferritin, low haemoglobin, and decreased TSAT.2,3,11 Furthermore, inflammation induces pro-inflammatory cytokines such as interleukin 6, which increases hepcidin production. This evidence concerns the gene HAMP and granular corneal dystrophy type II.