Neuropilin-1 (NRP-1) and neuropilin-2 (NRP-2) function as co-receptors for members of the VEGF receptor family and are proven to be involved in vascular growth, in developmental angiogenesis, and tumor-driven angiogenesis (Gelfand et al., 2014; Melincovici et al., 2018; Luo et al., 2020). The gene discussed is NRP2; the disease is neoplasm.