Out of the 52 publications identified using FISH for RET-rearrangement detection in lung cancers, 31 studies reported positive cases by break-apart FISH, which were also tested by at least one other molecular technique (mostly reverse transcription polymerase chain reaction [RT-PCR], next-generation sequencing [NGS], or NanoString) (Tables 1 and 2).11 The gene discussed is RET; the disease is lung cancer.