PLOD1 and central precocious puberty: Girls diagnosed with CPP within the 15 months before and the 15 months following the beginning of the COVID-19 pandemic. CPP was defined when breast development was evident before the age of 8 years with a baseline (LH) value of >0.3 mIU/mL and/or a stimulated LH value of >5 mIU/mL.