PCa cases, PRACTICAL consortium (n = 31,770; Fig. 4D); disease-free controls, the Malmö Diet and Cancer (MDC) Cohort (n = 2458; Fig. 4E) and The Västerbotten Intervention Project (VIP) Cohort (n = 4810; Fig. 4E) which all indicated lower total PSA (tPSA) levels for the rs17632542 SNP [C] allele. The gene discussed is PROS1; the disease is cancer.