In PCa cases, the f/t PSA ratio was 12.82 ± 0.22% for [TT] and 14.67 ± 0.70% for [CT] individuals (mean ± SEM, P = 0.006) and 21.5 ± 9.5% for individuals with [CC] genotypes (Fig. 4D). Here, KLK3 is linked to posterior cortical atrophy.