There are many other biological markers that may influence the prognosis of OPSCC, such as P53, Programmed Death receptor-1 (PD-1), Programmed Death Ligand-1 (PD-L1), Epidermal Growth Factor Receptor (EGFR), and Tumor-Infiltrating Lymphocytes (TILs) [27]. The gene discussed is TP53; the disease is neoplasm.