Next, we further analyzed the correlation between P4HA3 expression and immune marker genes, including CSF1R and CD86 (representing monocyte cells), IL10, CD68 and CCL2 (representing tumor-associated macrophage cells; TAM), PTGS2, NOS2 and IRF5 (representing M1 macrophage cells), VSIG4, MS4A4A and CD163 (representing M2 macrophage cells). This evidence concerns the gene IRF5 and neoplasm.