Regarding Th17 immunity against bacterial infection, Lgals3−/− mice exhibited normal clearance of C. rodentium, indicated by no obvious differences between WT and Lgals3−/− mice in body weight (Figure 5F), bacterial load (Figure 5G), colon length (Figure 5H), and colonic CD4+ T cells (Figure 5I), including CD4+IL17A+ cells (Figures 5J and S5B) and Tregs (Figure S5C). The gene discussed is CD4; the disease is bacterial infectious disease.