GPT and acute respiratory distress syndrome: Whilst the precise criteria used to define ALI may vary, the data regarding causes at a population level are relatively consistent when threshold ALT values are used to define the population by searching serology results, and suggest that DILI (predominantly APAP), ischaemic hepatitis, biliary obstruction and viral hepatitis account for the majority of ALI (Galvin et al. 2015; Con et al. 2019).