For instance, liver fibrosis is associated with increased levels of TGF-β1 (Fabregat et al. 2016), and various inflammatory cytokines, as well as decreased production of insulin-like growth factor (Liu et al. 2018), lecithin-cholesterol acyltransferase (Lu et al. 2022), and alterations in vitamin D and parathyroid hormone metabolism. The gene discussed is LCAT; the disease is Hepatic fibrosis.