Other variants in additional genes have been proposed as the cause of potential alterations in the reduction of the QT interval (ANK2_pArg3634Asp, PKP2_p.Asp26Asn and ABCC9_p.Arg633Cys) (Treat et al. 2021), but some of them have a MAF extremely high to be consider a causative variant of SQTS, and others require further studies to conclude a definite role in the SQTS or phenotype-like entities. Here, ANK2 is linked to Familial short QT syndrome.