It has been demonstrated that infertile males with variants in DNAH1, DNAH2, DNAH7, and DNAH8 have a favorable prognosis (Liu et al., 2020; Long et al., 2023; Wambergue et al., 2016; Li et al., 2019; Gao et al., 2021; Wei et al., 2021), while patients with variants in DNAH17 have poor outcomes after ICSI treatment (Whitfield et al., 2019; Zheng et al., 2021). The gene discussed is DNAH2; the disease is Infertility.