In addition, real-time qPCR analysis confirmed that Lin-CD34+CD38-/lowCD26+CD35- cells from CML patients at diagnosis displayed a strong signal for GAS2 (Figure 6B), one of the top genes from the CITE-seq BCR::ABL1+ LSC signature (Figure 4C). Here, CD34 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.