(A) Heatmap comparing antibody-derived tags (ADT) expression between BCR::ABL1+ and BCR::ABL1- cells within the Lin-CD34+CD38-/low primitive cluster across chronic myeloid leukemia (CML) patients (black = surface markers significantly up-regulated in BCR::ABL1- cells (log2 fold change < –1, p-value <.05); red = surface markers significantly up-regulated in BCR::ABL1+ cells (log2 fold change >1, p-value <.05); gray = non-significant change in ADT expression; white = surface marker was not present in the ADT panel used for the specific patient). The gene discussed is CD34; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.