To assess the level of quiescence between the BCR::ABL1+ LSCs and BCR::ABL1- HSCs, we sorted Lin-CD34+CD38-/lowCD45RA-CD26+CD35- and CD26-CD35+ single cells from two CML patients at diagnosis into individual wells and examined their division kinetics for 140 hr. This evidence concerns the gene CR1 and chronic myelogenous leukemia, BCR-ABL1 positive.