(C) A scheme for computational deconvolution of bulk transcriptomes from patients into constituent cell populations; using cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) derived gene signatures from Lin-CD34+ nBM as reference, an independent bulk CD34+ microarray dataset from CML patients (n=59 McWeeney et al., 2010) was deconvoluted into constituent cell populations using CIBERSORTx (Newman et al., 2019). This evidence concerns the gene CD34 and chronic myelogenous leukemia, BCR-ABL1 positive.