Myh9 mutants recapitulate similar disease phenotypes found in humans with MYH9-related diseases as all develop hematologic defects, and some develop kidney abnormalities, cataracts, and hearing loss, which have allowed for critical advances in the understanding of genotype-phenotype connections (Zhang et al. 2012; Suzuki et al. 2013). This evidence concerns the gene MYH9 and cataract.