While mutations in the MYH10 gene have not been associated with any known human genetic disorders, two human patients with de novo MYH10 mutations presented with clinical phenotypes including microcephaly, congenital diaphragmatic hernia, respiratory failure, and cardiac abnormalities, among others (Tuzovic et al. 2013; Gardner et al. 2020). The gene discussed is MYH10; the disease is respiratory failure.