ICGR15: indocyanine green retention rate at 15 min; CPC: Child-Pugh classification; MELD: model for end-stage liver disease; ALBI: albumin-bilirubin; ALICE: albumin-indocyanine green evaluation; HCC: hepatocellular carcinoma; Mets: metastatic tumor; CCC: cholangiocellular carcinoma; GB Ca: gallbladder carcinoma; Bile duct Ca: bile duct carcinoma. The gene discussed is ALB; the disease is hepatocellular carcinoma.