Risk factors associated with post-TB liver injury included pre-existing hepatitis (OR = 2.41, 95% CI: 1.16–6.08), previous TB treatment (OR = 2.64, 95% CI: 1.22–6.67), hypo-albuminemia (OR = 2.10, 95% CI: 1.53–2.88), HIV co-infection (OR = 2.72, 95% CI: 1.66–4.46), and CD4 count <200 mm3 in HIV-infected individuals (OR = 2.03, 95%CI: 1.26–3.27). This evidence concerns the gene CD4 and Hepatitis.