TCF4 is implicated in a broad spectrum of cognitive disorders (Del-Favero et al., 2002; Amiel et al., 2007; Brockschmidt et al., 2007; Zweier et al., 2007; Stefansson et al., 2009; Schizophrenia Psychiatric Genome-Wide Association Study Consortium, 2011; Cross-Disorder Group of the Psychiatric Genomics Consortium, 2013; Wray et al., 2018; Gelernter et al., 2019; Teixeira et al., 2021). The gene discussed is TCF4; the disease is schizophrenia.