Sun et al. suggested that early rehabilitation could influence the expression of serum inflammatory factors, such as vascular endothelial growth factor (VEGF), tumor necrosis factor-α (TNF-α), interleukin-10, and stromal cell-derived factor-1α, and motivate endothelial progenitor cells (12), thereby promoting endothelial formation and vascular regeneration in AIS (13). The gene discussed is TNF; the disease is androgen insensitivity syndrome.