LCN2 and glomerulosclerosis: Liu's study, which examined the nephrotoxicity effect of mercury chloride in mice, found that the compound significantly elevated serum levels of KIM-1 and NGAL as a result of kidney injury, and that HgCl2 inhibited the expression of renal transporter that elevated levels of SDF-1 and IL-6 as a result of kidney injury through glomerulosclerosis and albuminuria in mice [41].