In conclusion, our study indicates that, among people of European ancestry, genetically increased plasma levels of MIP-1β, IP-10, and RANTES are positively associated with an increased risk of HF, while genetically increased risk of HF is associated with elevated plasma levels of IL-17, FGF-basic, PDGF-BB, IFN-γ, and decreased levels of Eotaxin. The gene discussed is CXCL10; the disease is hydrops fetalis.