PLP1 and Pelizeaus-Merzbacher spectrum disorder: In the rare genetic disorder, Pelizaeus‐Merzbacher disease (PMD) (Nobuta et al., 2019; Elitt et al., 2020), we observed that PLP1 mutations lead to a state of ferroptosis in OLs, which could be attenuated by iron chelation (Nobuta et al., 2019).