It is suggested by some [13, 15, 16, 39], though not all [9, 14], of them that compared to the group of stable BMI within the normal range over time, the persistently high BMI group had higher risks of hypertension and diabetes, higher levels of systolic blood pressure (SBP), diastolic blood pressure (DBP), HbA1c, glucose, insulin, insulin resistance, total cholesterol, TG, LDL, and ApoB, as well as a lower level of HDL. The gene discussed is APOB; the disease is Hypertension.