LSD1 expression was detected in three glioma stem cell (GSC) lines (GSC1228, GSC222, and GSC316), as well as in differentiated glioma cell lines (LN229), and a normal neural stem cell line (F3), showing substantial but variable levels of both mRNA and protein expression (Supplementary Fig. S1C, D). This evidence concerns the gene KDM1A and central nervous system cancer.