Thereafter, we designed a multivariable logistic regression model including these variables, identifying mutilating changes (OR = 4.048, 95% confidence interval [CI] = 1.432–11.438, p = 0.008), RA duration ≥ 5 years (OR = 3.711, 95% CI = 1.279–10.769, p = 0.013), CRP level ≥ 3.8 mg/dL (OR = 2.187, 95% CI = 1.021–4.685, p = 0.044), and previous joint surgery (OR = 2.147, 95% CI = 1.122–4.108, p = 0.021) as significant independent predictive risk factors for the aggravation of VS (Table 3). Here, CRP is linked to rheumatoid arthritis.