GSPT1 and acute myeloid leukemia: Interestingly, FM-74-103 does not act by directly targeting NP but exerts its antiviral effects through the degradation of GSPT1, a protein previously linked to tumor diseases such as AML.646 This discovery not only expands the potential therapeutic applications of GSPT1 degraders but also supports the theory of using GSPT1 as a therapeutic target in these viral infections.