Additional application fields for CytoSorb include use of the device for removal of elevated levels of bilirubin and myoglobin in patients with life-threatening conditions, such as liver failure [12] or rhabdomyolysis [13], as well as the intraoperative removal of ticagrelor and rivaroxaban during cardiothoracic operations with cardiopulmonary bypass [14]. Here, MB is linked to Hepatic failure.