BDNF and Alzheimer disease: Treatment with the 5-HT1AR antagonist NAD-299 and the 5-HT2AR agonist TCB-2, either alone (5 μg/μl, respectively) or in combination (5 μg/0.5 μl, respectively), increased hippocampal BDNF levels and ameliorated memory deficits in AD rats [20].