PLEKHO1 and CD4+/CD56+ hematodermic neoplasm: Together, these data support a model in which MYB fusions contribute to transformation by activating the G2/M transition and in which MYB::PLEKHO1 is sufficient to cause BPDCN on its own because it can uniquely activate G2/M while simultaneously facilitating bypass of the G1/S cell cycle checkpoint.