MYB-TR and MYB::PLEKHO1 leukemias displayed a surface marker profile consistent with a myeloid or myeloid-dendritic progenitor origin, with consistent expression of CD11b and variable expression of CD11c (dendritic marker), BST2 (pDC marker), CD117 (stem/progenitor marker), and CD115 and CX3CR1 (myeloid-dendritic progenitor markers) (44) (Figure 4E and Supplemental Figure 4A). Here, MYB is linked to leukemia.