To investigate how BPDCN MYB fusions induce leukemic transformation of Hoxb8-FL progenitor cells, we performed CUT&RUN in MYB::PLEKHO1 leukemia cells using an anti-V5 antibody to detect chromatin occupancy of the exogenously expressed fusion protein (Supplemental Table 4). Here, HOXB8 is linked to leukemia.