FLOT2 and neoplasm: Of interest, the more robust enhancement of antitumor immunity in the global Flot2-null mouse as compared with mice with T cell–specific Flot2 deletion (Figure 1A and Figure 2A) also raises the possibility that Flot2 deletion in non–T cells (e.g., DCs, fibroblasts, endothelial cells) may contribute to tumor suppression.