PDK1 and cervicitis: Our previous study confirmed that the reactivation of PIWIL2 expression by HR‐HPV oncoproteins initiated cellular reprogramming, subsequently leading to TIC formation and cervical tumorigenesis.[6b] In this study, our data showed that PIWIL2 overexpression in HCBC cells and the normal keratinocyte cell line HaCaT via lentiviral transduction significantly upregulated PDK1 expression (Figure 2B,C).